Is karma yoga practical when even the people for whom we sacrifice consider it insane?

From Sunil Goel

can you please explain the essence/importance/relativity of  NISKAM KARMYOG in this material world where it is treated no more than INSANITY, even by those to whom you do the favour by sacrificing your own self – interests. in that case, how it will be better than fulfilling your own desires and making him a loser instead…..