Why fight a losing battle when we can fight a winning battle?
Shri Ishopanishad instructs us not to make one-sided attempts to win the struggle for existence. Everyone is struggling hard for existence, but the laws of material nature are so hard and fast that they do not allow anyone to surpass them. In order to attain a permanent life, one must be prepared to go back to Godhead.
The process by which one goes back to Godhead is a different branch of knowledge, and it has to be learned from revealed Vedic scriptures such as the Upanishads, Vedanta-sutra, Bhagavad-gita and Shrimad-Bhagavatam. To become happy in this life and attain a permanent blissful life after leaving this material body, one must study this sacred literature and obtain transcendental knowledge.
Ishopanishad Mantra 11 purport